Published Articles and Bibliometric indicators
Here you can find all the research articles, from the newest to the oldest, I have published throughout my career, along with the bibliometric indicators related to my research studies.
102
PublicationsProminent positions:
36 “First name”
15 “Last name”
36 Corresponding author
34
h-indexExpert in Carnosine
expertscape.comImpact over time
Publications
Citations
Carnosine Mitigates Cognitive Impairment and Dopamine Release in an Okadaic Acid-Induced Zebrafish Model with Alzheimer’s Disease-like Symptoms
Chern H, Caruso G, Desaire H, Jarosova R, (2025) ACS Chemical Neuroscience
Characterizing oxidative stress induced by Aβ oligomers and the protective role of carnosine in primary mixed glia cultures
Cardaci V, Di Pietro L, Zupan MC, Sibbitts J, Privitera A, Lunte SM, Caraci F, Hartley MD, Caruso G, (2025) Free Radic Biol Me […]
Development and in vitro characterization of new carnosine-loaded liposomal formulations
Russo S, Privitera A, Greco G, Di Pietro L, Cardaci V, Carota G, Sarpietro MG, Caruso G, (2024) J Liposome Res
Effects of carnosine on the embryonic development and TiO2 nanoparticles-induced oxidative stress on Zebrafish
Caruso G, Scalisi EM, Pecoraro R, Cardaci V, Privitera A, Truglio E, Capparucci F, Jarosova R, Salvaggio A, Caraci F, Brundo MV. (2023)
The Therapeutic Potential of Novel Carnosine Formulations: Perspectives for Drug Development
Bonaccorso A, Privitera A, Grasso M, Salamone S, Carbone C, Pignatello R, Musumeci T, Caraci F, Caruso G, The Therapeutic Potential of Novel Carnosine Formulations: […]
Carnosine Counteracts the Molecular Alterations Aβ Oligomers-Induced in Human Retinal Pigment Epithelial Cells
Caruso G, Fresta CG, Fidilio A, Lazzara F, Musso N, Cardaci V, Drago F, Caraci F, Bucolo C. Carnosine Counteracts the Molecular Alterations Aβ Oligomers-Induced in H […]
Characterization of Carnosine Effect on Human Microglial Cells under Basal Conditions
Caruso G, Privitera A, Saab MW, Musso N, Maugeri S, Fidilio A, Privitera AP, Pittalà A, Jolivet RB, Lanzanò L, Lazzarino G, Caraci F, Amorini AM.
Impact of buffer composition on biochemical, morphological and mechanical parameters: A tare before dielectrophoretic cell separation and isolation
Bonacci PG, Caruso G, Scandura G, Pandino C, Romano A, Russo GI, Pethig R, Camarda M, Musso N. Transl Oncol. 2023 Feb;28: […]
Effects of physical activity and exercise interventions on Alzheimer’s disease: an umbrella review of existing meta-analyses
López-Ortiz S, Lista S, Valenzuela PL, Pinto-Fraga J, Carmona R, Caraci F, Caruso G, Toschi N, Emanuele E, Gabelle A, Nisticò R, Garaci F, Lucia A, Santos-Lozano A. […]
Metabolic Signature of Energy Metabolism Alterations and Excess Nitric Oxide Production in Culture Media Correlate with Low Human Embryo Quality and Unsuccessful Pregnancy
Pallisco R, Lazzarino G, Bilotta G, Marroni F, Mangione R, Saab MW, Brundo MV, Pittalà A, Caruso G, Capoccia E, Lazzarino G, Tavazzi B, Bilotta P, Amorini AM.
Prenatal stress induces a depressive-like phenotype in adolescent rats: The key role of TGF-β1 pathway
Fidilio A, Grasso M, Caruso G, Musso N, Begni V, Privitera A, Torrisi SA, Campolongo P, Schiavone S, Tascedda F, Leggio GM, Drago F, Riva MA, Caraci F.
Colon Targeted Eudragit Coated Beads Loaded with Optimized Fluvastatin-Scorpion Venom Conjugate as a Potential Approach for Colon Cancer Therapy: In Vitro Anticancer Activity and In Vivo Colon Imaging
Ahmed OAA, Badr-Eldin SM, Caruso G, Fahmy UA, Alharbi WS, Almehmady AM, Alghamdi SA, Alhakamy NA, Mohamed AI, Aldawsari HM, Mady FM. J Pharm Sci. 2022 D […]
Surface-tailoring of emulsomes for boosting brain delivery of vinpocetine via intranasal route: in vitro optimization and in vivo pharmacokinetic assessment
Aldawsari HM, Badr-Eldin SM, Assiri NY, Alhakamy NA, Privitera A, Caraci F, Caruso G. Drug Deliv. 2022 Aug 8;29(1):2671-2 […]
The Therapeutic Potential of Carnosine as an Antidote against Drug-Induced Cardiotoxicity and Neurotoxicity: Focus on Nrf2 Pathway
Caruso G, Privitera A, Antunes BM, Lazzarino G, Lunte SM, Aldini G, Caraci F. Molecules. 2022 Jul 12;27(14):4452.
Dietary Phytoestrogen Intake and Cognitive Status in Southern Italian Older Adults
Giampieri F, Godos J, Caruso G, Owczarek M, Jurek J, Castellano S, Ferri R, Caraci F, Grosso G. Biomolecules 2022 May 30; […]
Unveiling the Hidden Therapeutic Potential of Carnosine, a Molecule with a Multimodal Mechanism of Action: A Position Paper
Caruso G. Molecules. 2022 May 20;27(10):3303.
Neuroprotective Effect of Carnosine Is Mediated by Insulin-Degrading Enzyme
Distefano A, Caruso G, Oliveri V, Bellia F, Sbardella D, Zingale GA, Caraci F, Grasso G. ACS Chmen Neurosci. 2022 May 18; […]
Adverse Events and Tolerability of Combined Durvalumab and Tremelimumab versus Durvalumab Alone in Solid Cancers: A Systematic Review and Meta-Analysis
Fahmy O, Ahmed OAA, Khairul-Asri MG, Alhakamy NA, Alharbi WS, Fahmy UA, El-Moselhy MA, Fresta CG, Caruso G, Caraci F. Biomedicines [...]
Polyphenols and neuroprotection: therapeutic implications for cognitive decline
Caruso G, Torrisi SA, Mogavero P, Currenti W, Castellano S, Godos J, Ferri R, Galvano F, Leggio GM, Grosso G, Caraci F. (2021) Pharm […]
Melittin and diclofenac synergistically promote wound healing in a pathway involving TGF-β1
Eid BG, Alhakamy NA, Fahmy UA, Ahmed OAA, Md S, Abdel-Naim AB, Caruso G, Caraci F. (2022) Pharmacol. Res. 175:105993.
[…]
The Role of Dielectrophoresis for Cancer Diagnosis and Prognosis
Russo GI, Musso N, Romano A, Caruso G, Petralia S, Lanzanò L, Broggi G, Camarda M. (2021) Cancers (Basel) 14 […]
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease
Caruso G, Grasso M, Fidilio A, Torrisi SA, Musso N, Geraci F, Tropea MR, Privitera A, Tascedda F, Puzzo D, Salomone S, Drago F, Leggio GM, Caraci F. (2021)
Oncological Response and Predictive Biomarkers for the Checkpoint Inhibitors in Castration-Resistant Metastatic Prostate Cancer: A Systematic Review and Meta-Analysis
Fahmy O, Alhakamy NA, Khairul-Asri MG, Ahmed OAA, Fahmy UA, Fresta CG, Caruso G. (2021) J. Pers. Med. 12:8.
Development of an Icariin-Loaded Bilosome-Melittin Formulation with Improved Anticancer Activity against Cancerous Pancreatic Cells
Alhakamy NA, Badr-Eldin SM, Alharbi WS, Alfaleh MA, Al-Hejaili OD, Aldawsari HM, Eid BG, Bakhaidar R, Drago F, Caraci F*, Caruso G*. (2021)
Biological Mechanism-based Neurology and Psychiatry: a BACE1/2 and Downstream Pathway Model
Hampel H, Caruso G, Nisticò R, Piccioni G, Mercuri NB, Giorgi FS, Ferrarelli F, Lemercier P, Caraci F, Lista S, Vergallo A. (2021) C […]
Updates on molecular and biochemical development and progression of prostate cancer
Fahmy O, Alhakamy NA, Rizg WY, Bagalagel A, Alamoudi AJ, Aldawsari HM, Khateb AM, Eldakhakhny BM, Fahmy UA, Abdulaal WH, Fresta CG, Caruso G*. (2021)
Ceftriaxone and melittin synergistically promote wound healing in diabetic rats
Alhakamy NA*, Caruso G*,*, Eid BG, Fahmy UA, Ahmed OAA, Abdel-Naim AB, Alamoudi AJ, Alghamdi SA, Al Sadoun H, Eldakhakhny BM, Caraci F*, Abdulaal WH. (2021)
The multimodal MOPr/DOPr agonist LP2 reduces allodynia in chronic constriction injured rats by rescue of TGF-β1 signalling
Fidilio A, Grasso M, Turnaturi R, Caruso G, Spitale FM, Vicario N, Parenti R, Spoto S, Musso N, Marrazzo A, Chiechio S, Caraci F, Pasquinucci L, Parenti […]
Altered follicular fluid metabolic pattern correlates with female infertility and outcome measures of in vitro fertilization
Lazzarino G, Pallisco R, Bilotta G, Listorti I, Mangione R, Saab MW, Caruso G, Amorini AM, Brundo MV, Lazzarino G, Tavazzi B, Bilotta P (2021)
Improving cognition with nutraceuticals targeting TGF-β1 signaling
Grasso M*, Caruso G*, Godos J, Bonaccorso A, Carbone C, Castellano S, Currenti W, Grosso G, Musumeci T, Caraci F (2021) Antioxidants […]
Time-restricted feeding is associated with mental health in elderly Italian adults
Currenti W, Godos J, Castellano S, Caruso G, Ferri R, Caraci F, Grosso G, Galvano F (2021) Chronobiol. Int. 38:1507-1516.
[…]
Piceatannol-loaded bilosome-stabilized zein protein exhibits enhanced cytostatic and apoptotic activities in lung cancer cells
Alhakamy NA*, Caruso G*, Al-Rabia MW, Badr-Eldin SM, Aldawsari HM, Asfour HZ, Alshehri S, Alzaharani SH, Alhamdan MM, Rizg WY, Allam AN (2021)
Carnosine protects macrophages against the toxicity of Aβ1-42 oligomers by decreasing oxidative stress
Caruso G*, Benatti C*, Musso N, Fresta CG, Fidilio A, Spampinato G, Brunello N, Bucolo C, Drago F, Lunte SM, Peterson BR, Tascedda F, Caraci F (2021)
Lung surfactant decreases biochemical alterations and oxidative stress induced by a sub-toxic concentration of carbon nanoparticles in alveolar epithelial and microglial cells
Caruso G*, Fresta CG, Costantino A, Lazzarino G, Amorini AM, Lazzarino G, Tavazzi B, Lunte SM, Dhar P, Gulisano M, Caraci F (2021) I […]
The therapeutic potential of carnosine/anserine supplementation against cognitive decline: a systematic review with meta-analysis
Caruso G, Godos J, Castellano S, Micek A, Murabito P, Galvano F, Ferri R, Grosso G, Caraci F (2021) Biomedicines 9:253.
[…]
Staphylococcus aureus ST228 and ST239 as models for expression studies of diverse markers during osteoblast infection and persistence
Bongiorno D*, Musso N*, Caruso G*, Lazzaro LM, Caraci F, Stefania S, Campanile F (2021) Microbiologyopen 10:e1178. [*co-f […]
Evaluation of the antiviral activity of sitagliptin-glatiramer acetate nano-conjugates against SARS-CoV-2 virus
Alhakamy NA, Ahmed OAA, Ibrahim TS, Aldawsari HM, Eljaaly K, Fahmy UA, Alaofi AL, Caraci F*,**, Caruso G*,** (2021) Pharmaceuticals […]
Cytotoxic and pro-apoptotic effects of a sub-toxic concentration of fluvastatin on OVCAR3 ovarian cancer cells after its optimized formulation to melittin nano-conjugates
Badr-Eldin SM, Alhakamy NA, Fahmy U, Ahmed OAA, Asfour HZ, Althagafi AA, Aldawsari HM, Rizg WY, Mahdi WA, Alghaith A, Alshehri S, Caraci F, Caruso G* (2021)
Association between time restricted feeding and cognitive status in older Italian adults
Currenti W, Godos J, Castellano S, Caruso G, Ferri R, Caraci F, Grosso G, Galvano F (2021) Nutrients 13:E191.
Pu […]
Different modulatory effects of four methicillin-resistant Staphylococcus aureus clones on MG-63 osteoblast-like cells
Musso N*, Caruso G*, Bongiorno D*, Grasso M, Bivona DA, Campanile F, Caraci F, Stefani S (2021) Biomolecules 11:E72. doi: […]
Antioxidant properties of second-generation antipsychotics: focus on microglia
Caruso G*,**, Grasso M*, Fidilio A*, Tascedda F, Drago F, Caraci F (2020) Pharmaceuticals (Basel) 13:457. [*co-first auth […]
Dihydrotanshinone, a natural diterpenoid, preserves blood-retinal barrier integrity via P2X7 receptor
Fresta CG*, Caruso G*, Fidilio A*, Platania CBM, Musso N, Caraci F, Drago F, Bucolo C (2020) Int. J. Mol. Sci. […]
Uncharacterized RNAs in plasma of Alzheimer’s patients are associated with cognitive impairment and show a potential diagnostic power
Barbagallo C, Di Martino MT, Grasso M, Salluzzo MG, Scionti F, Cosentino FII, Caruso G, Barbagallo D, Di Pietro C, Ferri R, Caraci F, Purrello M, Ragusa M (2020)
The encapsulation of febuxostat into emulsomes strongly enhances the cytotoxic potential of the drug on HCT 116 colon cancer cells
Fahmy UA, Aldawsari HM, Badr-Eldin SM, Ahmed OAA, Alhakamy NA, Alsulimani HH, Caraci F, Caruso G*. Pharmaceutics 12:E956. […]
New antipsychotic drugs for the treatment of agitation and psychosis in Alzheimer’s disease: focus on brexpiprazole and pimavanserin
Caraci F, Santagati M, Caruso G, Cannavò D, Leggio GM, Salomone S, Drago F (2020) F1000Res. […]
Microfluidics as a novel tool for biological and toxicological assays in drug discovery processes: focus on microchip electrophoresis
Caruso G*, Musso N, Grasso M, Costantino A, Lazzarino G, Tascedda F, Gulisano M, Lunte SM, Caraci F (2020)
Antidepressant drugs and physical activity: a possible synergism in the treatment of major depression?
Guerrera CV, Furneri G, Grasso M, Caruso G, Castellano S, Drago F, Di Nuovo S, Caraci F (2020) Front. P […]
Chitosan coated microparticles enhance simvastatin colon targeting and pro-apoptotic activity
Alhakamy NA, Fahmy UA, Ahmed OAA, Caruso G, Caraci F, Asfour HZ, Bakhrebah MA, Alomary MN, Abdulaal WH, Okbazghi SZ, Abdel-Naim AB, Eid BG, Ald […]
A path towards precision medicine for neuroinflammatory mechanisms in Alzheimer’s disease
Hampel HJ, Caraci F, Cuello AC, Caruso G, Nisticò R, Corbo M, Baldacci F, Toschi N, Garaci F, Chiesa PA, Verdooner SR, Akman-Anderson L, Hernan […]
Antioxidant therapies in traumatic brain injury
Di Pietro V, Yakoub KM, Caruso G, Lazzarino G, Signoretti S, Barbey AK, Tavazzi B, Lazzarino G, Belli A, Amorini AM (2020)
A new human blood-retinal barrier model based on endothelial cells, pericytes, and astrocytes
Fresta CG, Fidilio A, Caruso G, Caraci F, Giblin FJ, Leggio GM, Salomone S, Drago F, Bucolo C (2020) In […]
Modulation of pro-oxidant and pro-inflammatory activities of M1 macrophages by the natural dipeptide carnosine
Fresta CG, Fidilio A, Lazzarino G, Musso N, Grasso M, Merlo S, Amorini AM, Bucolo C, Tavazzi B, Lazzarino G*, Lunte SM, Caraci F, Caruso G* (20 […]
β-amyloid and oxidative stress: perspectives in drug development
Caruso G, Spampinato SF, Cardaci V, Caraci F, Sortino MA, Merlo S (2019) Curr. Pharm. Des. 2 […]
Pyruvate dehydrogenase and tricarboxylic acid cycle enzymes are sensitive targets of traumatic brain injury induced metabolic derangement
Lazzarino G, Amorini AM, Signoretti S, Musumeci G, Lazzarino G, Caruso G, Pastore FS, Di Pietro V, Tavazzi B, Belli A (2019)
The many faces of mitochondrial dysfunction in depression: from pathology to treatment
Caruso G, Benatti C, Blom JMC, Caraci F, Tascedda F (2019) Front. Pharmacol. 10:995.
[…]
Carnosine decreases PMA-induced oxidative stress and inflammation in murine macrophages
Caruso G*, Fresta CG Fidilio A, O’Donnell F, Musso N, Lazzarino G, Grasso M, Amorini AM, Tascedda F, Bucolo C, Drago F, La […]
Fluoxetine and vortioxetine reverse depressive-like phenotype and memory deficits induced by Aβ 1-42 oligomers in mice: a key role of transforming growth factor-β1
Torrisi SA, Geraci F, Tropea MR, Grasso M, Caruso G, Fidilio A, Musso N, Sanfilippo G, Tascedda F, Palmeri A, Salomone S, Drago F, Puzzo D, Leg […]
Fructose-1,6-bisphosphate protects hippocampal rat slices from NMDA excitotoxicity
Yakoub KM, Lazzarino G, Amorini AM, Caruso G, Scazzone C, Ciaccio M, Tavazzi B, Lazzarino G, Belli A, Di Pietro V (2019)
Pivotal role of carnosine in the modulation of brain cells activity: Multimodal mechanism of action and therapeutic potential in neurodegenerative disorders
Caruso G*, Caraci F*, Jolivet RB* (2018) Prog. Neurobiol. 175:35-53. [*corresponding authors […]
Inflammation as the common biological link between depression and cardiovascular diseases: can carnosine exert a protective role?
Caruso G*, Fresta CG, Grasso M, Santangelo R, Lazzarino G, Lunte SM, Caraci F (2019) Curr. Med. Chem. [...]
Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells: a key role of TGF-β1
Caruso G*, Fresta CG, Musso N, Giambirtone M, Grasso M, Spampinato SF, Merlo S, Drago F, Lazzarino G, Sortino MA, Lunte SM, Caraci F* (2019)
Optimization of a microchip electrophoresis method with electrochemical detection for the determination of nitrite in macrophage cells as an indicator of nitric oxide production
Siegel JM, Schilly KM, Wijesinghe MB, Caruso G, Fresta CG, Lunte SM (2018) Anal. Methods 11: […]
Sub-toxic human amylin fragment concentrations promote the survival and proliferation of SH-SY5Y cells via the release of VEGF and HspB5 from endothelial RBE4 cells
Caruso G*, Fresta CG, Lazzarino G, Distefano DA, Parlascino P, Lunte SM, Lazzarino G*, Caraci F (2018) I
Low-molecular weight compounds in human seminal plasma as potential biomarkers of male infertility
Lazzarino G, Listorti I, Muzii L, Amorini AM, Longo S, Di Stasio E, Caruso G, D’Urso S, Puglia I, Pisani G, Lazzarino G, Tavazzi B, Bilotta P ( […]
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target
Caraci F, Spampinato SF, Morgese MG, Tascedda F, Salluzzo MG, Giambirtone MC, Caruso G, Munafò A, Torrisi SA, Leggio GM, Trabace L, Nicoletti F […]
Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells
Fresta CG, Chakraborty A, Wijesinghe MB, Amorini AM, Tavazzi B, Lazzarino G*, Lunte SM, Caraci F, Dhar P*, Caruso G* (2018)
Microchip electrophoresis with laser-induced fluorescence detection for the determination of the ratio of nitric oxide to superoxide production in macrophages during inflammation
Caruso G, Fresta CG, Martinez-Becerra FA, Lopalco A, Johnson RT, de Campos RP, Siegel JM, Wijesinghe MB, Lazzarino G, Lunte SM (2017)
Carnosine modulates nitric oxide in stimulated murine RAW 264.7 macrophages
Caruso G, Fresta CG, Martinez-Becerra FA, Lopalco A, Johnson RT, de Campos RP, Siegel JM, Wijesinghe MB, Lazzarino G, Lunte SM (2017)
Monitoring carnosine uptake by RAW 264.7 macrophage cells using microchip electrophoresis with fluorescence detection
Fresta CG, Hogard ML*, Caruso G*, Costa EE, Lazzarino G, Lunte SM (2017) Anal. Methods 9:402 […]
Receptor-mediated toxicity of human amylin fragment aggregated by short- and long-term incubations with copper ions
Caruso G, Distefano DA, Parlascino P, Fresta CG, Lazzarino G, Lunte SM, Nicoletti VG (2017) Mol. Cell. […]
Identification of a human toll-like receptor (TLR) 8-specific agonist and a functional Pan-TLR inhibitor in 2-aminoimidazoles
Beesu M*, Caruso G*, Salyer AC*, Shukla NM, Khetani KK, Smith LJ, Fox LM, Tanji H, Ohto U, Shimizu T, David SA (2016)
Identification of adjuvantic activity of amphotericin B in a novel, multiplexed, poly-TLR/NLR high-throughput screen
Salyer AC, Caruso G, Khetani KK, Fox LM, Malladi SS, David SA (2016) PLoS One 11:e0149848. [...]
Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity
Beesu M, Caruso G, Salyer AC, Khetani KK, Sil D, Weerasinghe M, Tanji H, Ohto U, Shimizu T, David SA (2015)
Indirect detection of superoxide in RAW 264.7 macrophage cells using microchip electrophoresis coupled to laser induced fluorescence detection
de Campos RP, Siegel JM, Fresta CG, Caruso G, Fracassi da Silva JA, Lunte SM (2015) Anal. Bioanal. Chem […]
The role of copper(II) in the aggregation of human amylin
Sinopoli A, Magrì A, Milardi D, Pappalardo M, Pucci P, Flagiello A, Titman JJ, Nicoletti VG, Caruso G, Pappalardo G, Grasso G (2014)
Microchip electrophoresis with amperometric detection method for profiling cellular nitrosative stress markers
Gunasekara DB, Siegel JM, Caruso G, Hulvey MK, Lunte SM (2014) Analyst 139:3265-73.
P […]
An integrated microfluidic device for monitoring changes in nitric oxide production in single T-lymphocyte (Jurkat) cells
Metto EC, Evans K, Barney P, Culbertson AH, Gunasekara DB, Caruso G, Hulvey MK, Fracassi da Silva JA, Lunte SM, Culbertson CT (2013)
Monitoring intracellular nitric oxide production using microchip electrophoresis and laser-induced fluorescence detection
Mainz ER, Gunasekara DB, Caruso G, Jensen DT, Hulvey MK, Fracassi da Silva JA, Metto EC, Culbertson AH, Culbertson CT, Lunte SM (2012)
Microchip electrophoresis devices for the detection of nitric oxide: comparison of bulk cell and single cell analysis
Lunte SM, Gunasekara DB, Metto EC, Hulvey MK, Mainz ER, Caruso G, Fracassi da Silva JA, Jensen DT, Culbertson AH, Grigsby RJ, Culbertson CT (20 […]
Editorial Board member
Associate Editor For
Frontiers in Neuroscience | Neurodegeneration
Review Editor For
Frontiers in Neuroscience | Neuroenergetics, Nutrition and Brain Health
Frontiers in Psychiatry | Molecular Psychiatry
